POVIDONE-IODINE PLEURAL AND PERICARDIAL ALLERGY IN A POLYALLERGIC PATIENT
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We present the case of a 53 years old woman with a known history of hypersensitivity reaction to ACE-inhibitors and penicillin, who was admitted for a lower left lobe tumor. PET-CT scan revealed a left lower lobe mass. Preoperative fibrobronchoscopy was normal. A left lower lobectomy was carried out. After the removal of the lobe, a pleural washing with 500 ml 9% normal saline and 25 ml 5% povidone-iodine was performed. The patient instantly developed a pleural and pericardial diffuse petechial eruption. After several pleural washings with 9% sodium chloride and IV administration of epinephrine, the allergic reaction disappeared. No cutaneous allergic reaction was noticed during the patient OR skin prep with povidone-iodine.
This is a rare case of multiserous allergic reaction to a commonly used antiseptic, and, to our knowledge, little data is currently available in the literature on this topic. Still, it is a complication that should be taken into account in polyallergic patients.